摘要
目的:观察氟哌利多、托烷司琼预防腹腔镜阑尾切除术后恶心呕吐的临床疗效。方法:选择60例择期行全凭静脉麻醉下腹腔镜阑尾切除术的患者,随机分为A、B、C组,每组20例,分别在开始缝合前静脉注射0.9%氯化钠10mL(A组)、氟哌利多1.25mg(B组)、托烷司琼5mg(C组)。术毕清醒后拔管,观察记录术后24h患者发生恶心呕吐的情况。结果:B、C组的术后恶心呕吐发生率明显低于A组(P<0.05);B、C组比较差异无统计学意义(P>0.05)。结论:氟哌利多和托烷司琼均可显著降低腹腔镜阑尾切除术后恶心呕吐的发生率,二者疗效相当。
OBJECTIVE：To compare preventive effects of droperidol and tropisetron on nausea and vomiting after laparoscopic appendectomy.METHODS：60 patients with general anesthesia underwent elective laparoscopic appendectomy were randomly divided into group A,group B and group C （n=20）.Before suture,group A received 0.9% sodium chloride injection 10 mL,group B droperidol 1.25 mg,group C tropisetron 5 mg.Patients were extubated as them became conscious.The occurrence of nausea and vomiting 24 h after operation were observed and recorded.RESULTS：The occurrence rate of postoperative nausea and vomiting in group B and group C were significantly lower than in group A （P0.05）.There was no significant difference between group B and group C （P0.05）.CONCLUSION：Droperidol and tropisetron could significantly reduce the occurrence of nausea and vomiting after laparoscopic appendectomy.
出处
《中国药房》
CAS
CSCD
北大核心
2010年第28期2660-2661,共2页
China Pharmacy
