百草枯中毒大鼠肺组织环氧化酶-2和微血管密度的表达
被引量:2
摘要
百草枯中毒的特点是多器官功能损伤。肺是百草枯中毒主要的靶器官。百草枯中毒在早期常引起肺水肿、肺出血等为特征的肺损伤,在后期可进行性地发展为不可逆性肺间质纤维化。目前百草枯引起肺损伤的机制尚不清楚。还氧化酶2(COX-2)参与炎症和血管增生的病理过程,在哮喘、肺损伤、肺癌、肺纤维化中发挥重要作用。本研究探讨COX-2在百草枯中毒肺损伤中的作用及可能机制。
出处
《中华急诊医学杂志》
CAS
CSCD
北大核心
2010年第7期708-709,共2页
Chinese Journal of Emergency Medicine
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