摘要
目的比较使用低渗与等渗造影剂对糖尿病合并肾功能不全患者肾脏功能的影响。方法回顾性分析住院行冠状动脉造影及介入治疗126例糖尿病合并慢性肾功能不全患者的资料,着重比较低渗与等渗造影剂对糖尿病合并肾功能不全患者肾脏功能的影响。根据使用的造影剂将患者分为低渗造影剂(LOCM)组,86例;等渗造影剂(IOCM)组,40例,比较两组患者的临床特点、手术前后血清肌酐及估算肾小球滤过率变化、造影剂肾病的发生率。结果两组在临床特点、手术前后血清肌酐差值[6.4(38.5)vs.6.0(48.9),P>0.05]及肾小球滤过率差值[0.9(9.7)vs.0.9(8.8),P>0.05]的均值及造影剂肾病的发生率(24.4%vs.25.0%,P=0.944)比较,差异无统计学意义。结论对于糖尿病合并肾功能不全患者,两种造影剂对肾功能影响相当。
Objectives To compare the renal function injury between low-osmosis contrast medium and iso-osmosis contrast medium on the diabetics with chronic renal failure.Methods Data of 126 patients who had undergone coronary angiography or intervention were retrospectively analyzed.These 126 cases were divided into low-osmosis contrast medium （LOCM）group（n=86）and iso-osmosis contrast medium （IOCM） group（n=40）.Clinical features,pre-and postoperative difference of serum creatinine and estimated glomerular filtration rate （eGFR）,the rate of contrast-induced nephropathy （CIN） of the 2 groups were compared.Results There were no statistical significance in the clinical features,the pre- and postoperative difference of serum creatinine[6.4（38.5） vs.6.0（48.9）,P〉0.05],eGFR[0.9（9.7） vs.0.9（8.8）,P〉0.05] and CIN rate （24.4% vs.25.0% ,P=0.944）.Conclusions Low-osmosis and iso-osmosis contrast medium may have the same renal function injury on the diabetics with chronic renal failure.
出处
《岭南心血管病杂志》
2010年第2期130-132,共3页
South China Journal of Cardiovascular Diseases
关键词
造影剂肾病
糖尿病
慢性肾功能不全
血管造影术
低渗造影剂
等渗造影剂
contrast-induced nephropathy
diabetes mellitus
chronic renal failure
angiography
low-osmosis contrast medium
iso-osmosis contrast medium
