摘要
目的探讨坎地沙坦酯联合比索洛尔治疗原发性高血压患者血压晨峰的临床疗效。方法将我院2007年10月～2009年10月96例原发性高血压病患者随机分为3组,坎地沙坦酯联合比索洛尔治疗组、坎地沙坦酯治疗组、比索洛尔治疗组,观察服药前及服药后9周的清晨血压变化。结果联合治疗组、坎地沙坦酯组、比索洛尔组晨峰下降的幅度分别为(△SBP:△DBP,35.69±1.65、15.91±0.78;29.42±1.32、13.61±0.85;26.63±1.24、13.53±0.84),联合治疗组晨峰下降幅度高于坎地沙坦酯组、比索洛尔组(P<0.05);坎地沙坦酯组、与索洛尔组晨峰下降幅度无显著差异(P>0.05),联合治疗组控制血压晨峰的疗效优于其它组(P<0.05)。结论坎地沙坦酯联合比索洛尔可以有效地控制原发性高血压患者血压晨峰现象。
Objective This study was to evaluate the effects of combining Candesartan and Bisoprolol on blood pressure morning surge of essential hypertension patients.Methods ninty-six essential hypertension patients from October 2007 to October 2009 were divided into three groups,combinant group,Candesartan gorup,Bisoprolol gorup,then analyzing the results of variety blood pressure morning surge.Results There were significantly differences in blood pressure morning surge between combinant group（△SBP：△DBP,35.69±1.65,15.91±0.78）and Candesartan group（△SBP：△DBP,29.42±1.32,13.61±0.85）,Bisoprolol gorup（△SBP：△DBP,26.63±1.24,13.53±0.84）.The Candesartan group showed no significantly differences with Bisoprolol group in blood pressure morning surge（P0.05）.Conclusion Combinant of Candesartan and Bisoprolol showed great therapeutic effect on blood pressure morning surge.
出处
《当代医学》
2010年第18期64-66,共3页
Contemporary Medicine
关键词
血压晨峰
坎地沙坦酯
比索洛尔
blood pressure morning surge
candesartan
bisoprolol
