摘要
组织因子（TF）是生理性凝血过程中最重要的启动因子.TF除了参与凝血过程外,还可与凝血凼子Ⅶ结合通过多种信号传导,在肿瘤生长、血管生成及侵袭、转移过程中发挥重要作用.近年来,针对TF的靶向治疗取得了令人瞩目的进展,显示出对肿瘤组织及转移灶的明显抑制作用.
Tissue factor（TF）is the most important factor in the physiological coagulation process.TF also plays important roles in tumor growth,angiogenesis,invasion and metastasis by combining with factor VII.In recent years,targeted therapy for the TF has made remarkable progress,showing its significant inhibition of tumor tissue and metastasis.
出处
《国际外科学杂志》
2010年第7期469-472,共4页
International Journal of Surgery
基金
兰州市科技发展计划项目（No.2008-1-80）
关键词
组织因子
肿瘤
侵袭
靶向治疗
Tissue factor
Tumor
Invasion
Targeted therapy
