摘要
目的回顾性分析充血性心力衰竭(CHF)合并阻塞型睡眠呼吸暂停低通气综合征(OSAHS)的特点。方法对26例CHF合并OSAHS患者的临床资料进行回顾性分析。结果 26例患者均为肥胖患者,夜间最低血氧饱和度(SaO2)≤84%者23例(88%);氧合指数(PaO2/FiO2)≤300mmHg(1mmHg=0.133kPa)者25例(96.15%),其中≤200mmHg者4例(15.38%)。在给予慢性心力衰竭最佳药物治疗下,23例患者均给予晚间双水平呼吸道正压通气(BiPAP)治疗,治疗后夜间最低SaO2及PaO2/FiO2均较治疗前改善(P<0.01),患者自主症状及6min步行试验均得到改善。结论 CHF合并OSAHS患者是普遍存在的,但又经常未被重视,临床上争取早诊断、早治疗对降低其病死率有重要意义。
Objective To retrospectively analyze the clinical features of congestive heart failure （CHF） patients with obstructive sleep apnea-hypopnea syndrome（OSAHS）. Methods The clinical data of 26 patients with CHF and OSAHS was retrospectively analyzed. Results All these 96 patients were obese, 23 （88%） patients＇minimum arterial oxygen saturation （SaO2） during the night were ≤84%, 25 （96.15 % ） patients＇oxygenation index（ PaO2/FiO2 ） were ≤300 mm Hg（ 1 mm Hg =0. 133 kPa）, and 4（ 15.38% ） of the 25 patients＇PaO2/FiO2 were ≤200 mm Hg. 23 patients received bilevel positive airway pressure（ BiPAP） in the evening with the optimal medical therapy for chronic heart failure. The PaO2/FiO2 and minimum SaO2 during the night were improved after treatments （ P 〈 0.01 ）. Patients＇ symptom and six-minute walk test were improved. Conclusion OSAHS is highly prevalent and frequently unrecognized in patients with CHF, the diagnosis and active measures in early stage contribute to decrease its mortality.
出处
《中华肺部疾病杂志（电子版）》
CAS
2010年第1期30-33,共4页
Chinese Journal of Lung Diseases(Electronic Edition)
