摘要
目的观察微波对区域性／全身低热疗法后引起的血压、脉搏、心电图的改变。方法对５４例晚期肿瘤患者用大功率９１５微波机加热下胸或脐周围持续１２０～１８０ｍｉｎ，食管或直肠温度达４０℃以上，１２０～１８０ｍｉｎ。热疗前后测血压、心率及心电图。结果患者有不同程度的心动增速，血压轻度增加。热疗前ＥＣＧ正常的４４例，热疗后有１６例（３６％）出现不同程度的心肌缺血；热疗前ＥＣＧ有轻度缺血性改变的１０例，热疗后８例ＥＣＧ改变加重，２例ＥＣＧ改变消失。热疗１２０分钟，ＥＣＧ出现异常的有２５％（６／２４），１５０分钟以上时有５０％（１０／２０）。均于３～４周后恢复，无严重后果，ＥＣＧ异常的发生率似与被加温的部位无关。结论全身热疗可加重心肌负担，慢性心肌供血不足的病人要慎用。
ObjectiveTo observe the pulse,blood pressure and ECG changes after regional/ whole body low hyperthemia.Methods 54 advanced cancer patients were heated by 600～800W microwave power to the lower chest or midabdominal region for 120～180min.The temperature in rectum or esophagus is higher than 40℃ to certain time.The pulse,blood pressure and ECG are taken before and after traetment.Results In 44 cases with normal ECG findings,16(36%) cases were found with more or less ST depression in their ECG.In 10 cases with mild abnormal EGC findings,ST depression was found in multiple channels in 8 cases,while in 2 cases the abnormal finding was no more exist.Patients heated for 120 minutes,25%(6/24) of them were found with abnormal ECG after treatment,while patients heated for 150-180min,50%(10/20).The incidence of abnormal ECG seems with no relationship to sites of heating.No serious side effect was found in this group.Conclusion The burden of cardiac muscle may be aggravated by the whole body hyperthermia.The invalids with blood short supply of cardiac muscle must be careful for this therapy.
关键词
肿瘤
热疗法
心电图
心肌缺血
Carcinoma Regional/ whole body hyperthermia ECG Cardiac ischemia
