摘要
目的:探讨长沙地区手足口病的病原学特征,为当地的疾病预防和控制提供科学依据。方法:使用肠道通用和EV71、CAl6特异性引物,对2009年长沙市的115例手足口病患者的疱疹液、粪便、咽拭子标本,进行RT-PCR鉴定,并对手足口病疫情开展监测,采用流行病学方法对结果进行统计分析。结果:在采集到标本的115例患者中,84例患者检测结果为阳性,其中19例检测为EV71病毒核酸阳性(22.62%);30例检测CAl6阳性(35.71%);35例检测到其他肠道病毒(41.67%)。阳性标本中男女性别比为(1.27:1),发病年龄主要集中1-5岁儿童(90.47%),尤其是在3岁组(34.52%);发病季节主要集中于4-8月。结论:在长沙地区手足口病易发于1-5岁儿童,应在春夏季重点加强这一人群的预防和控制措施。
Objective： To reveal the etiological characteristics of hand-foot-mouth disease （HFMD） in Changsha and provide scientific basis for the control of this disease. Methods：Specimen, including herpes fluid,stool and throat swabs, were collected from 115 suspected cases of HFMD in Changsha. All the specimens were tested by RT-PCR assay with one and two specific primer for VPI genes of EV71 and CA16, respectively. The results were statistically analyzed by epidemiological methods. Results：In 115 suspected cases, 84 were identified HFMD positive, including 19 EV71 positive （22.62%） 30 CA16 positive （35.71%） and 35 other enterovirus positive （41.67%）. The sex ratio in HFMD positive patients was 1.27：1. The age of susceptible population was 1 to 5 yeas old （90.47%）, especially in 3 years old group （34.52%）. The high-occurrence season of HFMD in Changsha was from April to August, 2009. Conclusion： Children （1 to 5 years old） is susceptible to HFMD,so extra protections should be imposed to susceptible population from April to August in Changsha.
出处
《现代生物医学进展》
CAS
2010年第10期1932-1934,1948,共4页
Progress in Modern Biomedicine
基金
长沙市<食品安全危险生物因素快速检测方法的建立及成果应用研究>(K0902167-31)
