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腹腔镜保守性手术联合药物防治输卵管妊娠后持续性异位妊娠的临床研究 被引量:7

The clinical research on the prevention of persistent ectopic pregnancy with combination of laparoscopic conservative surgery and mifepristone in patients with tubal pregnancy
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摘要 目的探讨用米非司酮预防腹腔镜下保守性手术治疗输卵管妊娠后持续性异位妊娠(PEP)的治疗效果。方法对58例输卵管妊娠患者行腹腔镜下保守性手术,应用米非司酮50mg,每日2次。结果手术中无一例发生PEP。术前术后用米非司酮50mg,每日2次,能成功预防腹腔镜下保守性手术治疗输卵管妊娠后PEP的发生,避免了术前因为警惕PEP发生而对患者进行筛查,扩大了保守性手术治疗的范围。结论术前术后应用米非司酮,减少了患者痛苦,且无明显不良反应,有推广价值。 Objective To study the effects of combination of laparoscopic conservative surgery and mifepristone to prevent persistent ectopic pregnancy (PEP) in patients with tubal pregnancy. Methods Fifty eight cases with tubal pregnancy began to take the mifepristone (50 mg, twice a day). Result There was no PEP case was found in these patients. The PEP could be prevented by using mifepristone (50 mg, twice a day) before and after the laparoscopic conservative surgery in cases with tubal pregnancy, could avoid the cases screening and expanding the scope of conservative operation. Conclusion Preoperative and postoperative application of mifepristone could reduce the pains of patients, and no significant side effects were found, so this method is worth popularizing.
作者 周乃菊
出处 《实用医技杂志》 2010年第7期611-612,共2页 Journal of Practical Medical Techniques
关键词 腹腔镜检查 妊娠 异位 米非司酮 Laparoscopy Pregnancy, ectopic Mifepristone
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  • 1Yao M,Tulandi T. Current status of surgical and nonsurgical management of ectopic pregnancy. Fertil Steril, 1997,67 : 421-433. 被引量:1
  • 2Silver PD, Schaper AM, Rooney B. Reproductive outcome after 143 laparoscopic procedures for ectopic pregnancy. Obstet Gynecol, 1993,81 : 710-715. 被引量:1
  • 3Fernandez H, Marchal L, Vincent Y. Fertility after radical surgery for tubal pregnancy. Fertil Steril, 1998,70:680-686. 被引量:1
  • 4Shalev E,Peleg D, Bustan M, et al. Limited role for intratubal methotrexate treatment of ectopic pregnancy. Fertil Steril, 1995,63(1):20-24. 被引量:1

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