摘要
目的观察双水平气道正压无创通气治疗慢性阻塞性肺疾病(COPD)急性发作合并呼吸衰竭的疗效。方法 58例COPD急性发作合并呼吸衰竭患者随机分为治疗组28例与对照组30例,对照组给予常规药物及吸氧等对症支持治疗;治疗组在此基础上给予无创正压通气治疗。观察两组治疗前后的临床指标和血气分析情况。结果治疗组与对照组治疗前的基本情况、生命体征、血气情况差异无统计学意义(P>0.05)。治疗3d后治疗组pH、PaO2、PaCO2等指标明显改善(P<0.05)。结论无创正压通气治疗COPD急发合并呼吸衰竭,能更快缓解患者的临床症状,降低PaCO2、提高PaO2。其疗效优于常规治疗方法。
Objective Observation of bi-level positive airway pressure non-invasive ventilation in the treatment of acute exacerbation chronic obstructive pulmonary disease（AECOPD）with respiratory failure combined.Methods 58 cases of AECOPD with respiratory failure were randomly divided into treatment group（28 cases）and the control group（30 patients）.The control group received conventional drugs and oxygen and other symptomatic supportive care.On this basis,the treatment group was given non-invasive positive pressure ventilation in the treatment.The clinical indicators and blood gas analysis of the situation were observed before and after treatment.Results Before the treatment the basic situation of vital signs,blood gas was no significant difference between the treatment group and control group（P0.05）.Treatment for 3 days later,the level of-pH,PaO2,PaCO2 and other indicators improved significantly in the treatment group（P0.05）.Conclusion For AECOPD with respiratory failure,non-invasive positive pressure ventilation can quickly ease the patient′s clinical symptoms,reduce the level of PaCO2,increased the level of PaO2.Its efficacy is superior to conventional treatment methods.
出处
《四川医学》
CAS
2010年第6期794-795,共2页
Sichuan Medical Journal
关键词
无创通气
慢性阻塞性肺疾病
呼吸衰竭
non-invasive ventilation
chronic obstructive pulmonary disease
respiratory failure
