摘要
在心肌损伤中,心肌细胞凋亡信号通路包括了依赖于caspase的信号途径和不依赖于caspase的信号途径,以及炎性反应、氧化及自噬等信号机制的交联和激活信号途径,心肌细胞的凋亡信号通路决定着心肌的生存与死亡,对心肌损伤的发生、发展及预后产生重要影响。
The cardiac myocyte apoptosis signal transduction includes caspase-dependend pathways and caspase-independend pathway,and also involve crosstalk or interaction with the inflammation,oxidation stress,autophagy and other mechanisms signal networks in myocardium injury.The apoptotic signaling pathway control the life cycle of cardiac myocyte in the heart.It has a great impact on the development and prognosis of the myocardium injury.
出处
《基础医学与临床》
CSCD
北大核心
2010年第7期775-777,共3页
Basic and Clinical Medicine
基金
国家自然科学基金(C030313)
关键词
信号传导
凋亡
心肌细胞
心肌损伤
signal transduction
apoptosis
myocytes
myocardium injury
