摘要
为了探讨原发性胃肠道恶性淋巴瘤的临床特点、诊断和治疗方法,回顾性分析我院38例原发性胃肠道恶性淋巴瘤患者的临床资料。38例患者中胃恶性淋巴瘤17例,小肠恶性淋巴瘤12例,结肠淋巴瘤9例,临床表现主要为腹痛、腹部肿块、消瘦和贫血等,霍奇金病4例,非霍奇金淋巴瘤34例;按照1994年Arbor分期标准,ⅠE期10例,ⅡE期16例,ⅢE期8例,ⅣE期4例;手术加化疗治疗23例,单纯化疗10例,手术加放疗5例;总5年生存率为57.9%(22/38)。初步研究结果提示,原发性胃肠道恶性淋巴瘤的临床表现缺乏特异性,早期诊断困难,误诊率高,内镜病理活检联合CT是诊断胃肠恶性淋巴瘤的主要手段,运用手术及术后放、化疗等综合治疗措施可提高患者的生存率。
The objective of this study was to investigate the clinical features,diagnosis and treatment of primary gastrointestinal malignant lymphoma.The clinical data of 38 cases of primary gastrointestinal malignant lymphoma were retrospectively analyzed.Among the 38 patients,there were 17 cases of gastric malignant lymphoma,12 cases of malignant lymphoma of the small intestine,and 9 cases and colon lymphoma,whose clinical manifestations were abdominal pain,abdominal mass,weight loss,and anemia.There were 4 cases of Hodgkin＇s disease and 34 cases of non-Hodgkin＇s lymphoma disease.Accordance with the 1994 Arbor staging criteria,there were 10 cases of Ⅰ E period,16 cases of Ⅱ E period,8 cases of Ⅲ E phase and 4 cases of Ⅳ E period;There were 23 cases treated with surgery plus chemotherapy,10 cases treated with chemotherapy alone,and 5 cases treated with surgery plus radiotherapy.The overall 5-year survival rate was 57.9% （22/38）.In conclusion,primary gastrointestinal malignant lymphoma lacks specific clinical manifestations,the early diagnosis is difficult,and the misdiagnosis rate is high.The joint of CT endoscopic biopsy is the primary means of diagnosis.The use of surgery,postoperative radiotherapy,chemotherapy and other comprehensive treatment measures can improve the survival rate of the patients.
出处
《中华肿瘤防治杂志》
CAS
2010年第8期629-630,共2页
Chinese Journal of Cancer Prevention and Treatment
关键词
胃肠肿瘤/诊断
淋巴瘤/诊断
胃肿瘤/治疗
gastrointestinal neoplasms/diagnosis
lymphona/diagnosis
stomach neoplasms/therapy
