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新型植骨材料BMG的研制 被引量:1

A New Bone-grafting Material BMG
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摘要 1961年,Goldhaber发现活性骨组织可以通过扩散的微孔滤膜诱导骨组织形成[1]。Uris等人从骨基质中分离出具有诱导活性的蛋白—骨诱导蛋白(BMP),目前临床上已用它来治疗骨折、骨缺损等疾病。故我们研究用小牛四肢骨制备BMG,试图研究临床应用... OBJECTIVE:To investigate into the inducing activity of the bone matrix gelatin obtained from limb bones of new-born clves on mice and rabbits.METHOD:BMG was transplanted into the mouse vertebra at the hip and the bilateral sides of the spinal column at the back of rabbits.RESULT:Tissue slices showed the presence of active osteoid tissues and calcified bones developing into osteocytes.CONCLUSION:The BMG obtained from calf bones is expected to be used in clinical practice.
出处 《南京中医药大学学报》 CAS CSCD 1999年第2期114-114,共1页 Journal of Nanjing University of Traditional Chinese Medicine
关键词 骨基质明胶BMG 骨诱导蛋白BMP 脱钙骨基质DBM Bone matrix gelatin,bone inducing protein,decalcification bone matrix
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  • 1K. Amitani M. D.,Y. Nakata. Studies on a factor responsible for new bone formation from osteosarcoma in mice[J] 1975,Calcified Tissue Research(2):139~150 被引量:1

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  • 1Caplan AL. Mesenchymal stem cells[J]. J Orthop Res, 1991,9:641. 被引量:1
  • 2Kadiyala S, Young RG, Thiede MA, et al. Culture expanded canine mesenchymal stem cells possess osteochondrogentic potential in vivo and in vitro[J]. Cell Transplant, 1997, 6:125- 126. 被引量:1
  • 3Grande DA, Southerland SS, Manji R, et al. Repair of articular cartilage defects using mesenchymal stem cells[J]. Tissue Eng, 1995,1 : 345 - 353. 被引量:1
  • 4Johnstone B, Hering TM, Caplan AL, et al. In vitro chrondrogenesis of bone marrow- derived mesenchymal progenitor cell[J]. Exptl Cell Res, 1998,238:265 - 272. 被引量:1
  • 5Worster AA, Nixon AJ, Brower- Toland BD, et al. Effect of transforming growth factor β1 on chondrogenic differentiation of cultured equine mesenchymal stem cell[J]. Am J Vet Res, 2000,61:1003. 被引量:1
  • 6Berry L, Grani ME, Mcclure J,et al. Bone-marrow-derived chondrogenesis in vitro[J]. J Cell Sci,1992,101: 333-342. 被引量:1
  • 7Ahmed N, Sammons J, Carson RJ, et al. Effect of bone morphogenetic protein-6 on haemopoietic stem cell and cytokine production in normal human bone marrow stroma[J]. Cell Biology International, 2001,25 (5) : 429 - 435. 被引量:1
  • 8Urist MR, Sato K, Brownell AG, et al. Human bone morphogenetie protein(hBMP) [J]. Proc Soc Exp Biol Med, 1983,173 : 194. 被引量:1
  • 9Reddi H. Bialogical principles of bone induction[J]. Orthop Clin North Am; 1987,18(2) : 207 - 215. 被引量:1
  • 10Hendrickson DA, Nixon AJ, Erb HN, et al. Phenotype and biological activity of neonatal equine chondrocytes cultured in a three - dimensional fibrin matrix[J]. Am J Vet Res, 1994, 55: 410-414. 被引量:1

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