摘要
目的观察扩张型心肌病患者窦性心律震荡(HRT)的特征及其对预后的影响。方法选择扩张型心肌病并室早的患者366例作为试验组,选择同期有室早而无器质性心脏病50例作对照组,分别检测窦性心率震荡的初始(TO)和窦性心率震荡的斜率(TS),试验组按照HT与TS值再分成2个亚组:试验Ⅰ组,HRT0:TO<0与TS>3.0ms/RR间期;试验Ⅱ组,HRT1:TO≥0与TS≤3.0ms/RR间期;对照组,HRT2:TO≥0与TS≤3.0ms/RR间期,分别对不同心功能分级、存活组及死亡组进行分析。结果随着心功能的恶化,其心律震荡钝化现象愈加明显,其心脏性死亡明显增加。无论心功能正常与否,TO、TS与室性期前收缩的配对间期无关。结论扩张型心肌病患者存在室早后窦性心率震荡减弱或消失现象,窦性心率震荡对其预后有一定的预测价值。
Objective To study the change and prognostic value of heart rate turbulence （HRT） in patients with dilated cardiomyopathy （DCM）. Methods Three hundreds sixty six dilated cardiomyopathy patients with ventricular premature beat were enrolled as trial group, 50 cases with ventricular premature beat but not with heart disease as control group. All patients were divided into different cardiac function groups. The turbulence onset （TO） and turbulence slope （TS） of HRT were inspected individually and the categories of HRT between groups were analyed. The HRT was categoried into three： HRT0 with TO 〈0 and TS 〉 3.0 ms/RR interval as trial Ⅰ group, HRT1 with TO≥0 and TS ≤ 3.0 ms/RR interval as trial Ⅱ group, HRT2 with TO ≥ 0 vs TS ≤ 3.0 ms/RR interval as control group. Results With the deterioration of cardiac function, heart rate turbulence passivation phenomenon increasingly evident, their cardiac death increased significantly. Regardless of cardiac function was normal or not. There was no significant correlation between TO, TS and the coupling interval of ventricular extrasystole. Conclusion Decreasing and disappearing phenomenon of HRT are observed in dilated cardiomyopathy patients. HRT shows definite value as a predictor index of the mortality of dilated cardiomyopathy.
出处
《中国临床药理学杂志》
CAS
CSCD
北大核心
2010年第6期410-412,共3页
The Chinese Journal of Clinical Pharmacology
关键词
扩张型心肌病
窦性心律震荡
预后
dilated cardiomyopathy
heart rate turbulence
prognosis
