摘要
【目的】探讨急性脑梗死患者血清IL-6、IL-8水平与脑梗死面积及发病机制的关系。【方法】测定50例脑梗死患者及对照组血清IL-6、IL-8水平，并分析与脑梗死面积及发病机制的关系。【结果】①急性脑梗死组的血清IL-6、IL-8水平均明显高于对照纽；②大面积梗死患者的血清IL-6、IL-8水平均明显高于中、小面积梗死患者。【结论】炎症过程参与了脑血管病变；IL-6、IL-8水平与脑缺血程度以及脑的小血管病变范围密切相关。IL-6、IL-8是预测脑梗死患者病情严重程度的重要生化指标。
[Objective]To investigate the relationship between the levels of serum IL-6 and IL-8 in acute cerebral infarction patients and the infarction size and pathogenesis. [Methods]Fifty cases of acute cerebral infarction and 50 normal controls were tested for serum IL-6 and IL-8, and their correlation was analyzed. [Results] The levels of serum IL-6 and IL-8 of patients with cerebral infarction were significantly higher than those in controls. The levels of serum IL-6 and IL-8 in a large area of cerebral infarction were significantly higher than those in middle and small area of cerebral infarction. [Conclusion] Inflammatory process involves in the small vascular lesion in brain. The levels of serum IL-6 and IL-8 are closely correlated with the degree of cerebral ischemia. IL6 and IL-8 are important biological markers for predicting the severity of cerebral infarction.
出处
《医学临床研究》
CAS
2010年第6期1038-1039,1042,共3页
Journal of Clinical Research
