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TIPS中应用8mm直径ePTFE覆膜支架的临床研究

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摘要 目的 评价在经颈静脉肝内门体静脉分流术(TIPS)中应用8mm直径膨化聚四氟乙烯(ePTFE)覆膜支架的临床效果.方法 对21例伴有食管胃底静脉曲张破裂出血和(或)难治性腹水的门脉高压症患者行TIPS术,术中应用8mm直径的ePTFE覆膜支架,术后观察临床症状改善程度,并进行定期影像学和实验室检查,来评价治疗的效果.结果 所有患者均成功完成TIPS术,技术成功率100%,术中没有并发症的发生.术后随访3~32(14.6±7.6)个月,新出现肝性脑病或原有肝性脑病加重的发生率为0;再次出血率(3/19)15.8%;腹水改善及治愈率为66.7%;死亡率14.3%(3/21).结论 在经颈静脉肝内门体分流术中应用8 mm直径ePTFE覆膜支架在保证有效分流量,提高术后分流道开通率的同时,可以降低肝性脑病的发生率.
作者 梁松年 徐克
出处 《中国医师杂志》 CAS 2010年第6期792-795,共4页 Journal of Chinese Physician
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