摘要
目的:探讨放射性131I治疗甲状腺功能亢进症(甲亢)合并肝功能损害的临床价值。方法:对71例甲亢合并肝功能损害患者的临床资料进行回顾性分析。结果:131I治疗后甲状腺激素水平和肝功能各项指标均明显改善,与治疗前差异均有统计学意义(P<0.05~P<0.01)。治疗后6个月,59例甲亢治愈,61例肝功能完全恢复正常,10例肝功能指标明显下降,5例出现甲状腺功能减退症。结论:131I是甲亢合并肝功能损害安全有效的治疗方法。
Objective：To assess the effect of 131I therapy on patients with hyperthyroidism complicated with hepatic dysfunction.Methods：Clinical data of 71 cases of hyperthyroidism with liver damage were studied retrospectively.Results：Serum levels of FT3,FT4,aspartate aminotransferase,alanine aminotransferase,alkaline phosphatase,total bilirubin were obviously improved after 131I treatment（P0.05 to P0.01）.Of the 71 cases,the liver function of 61 turned normal and 10 showed significant efficacy after 6 months,5 presented with hypothyroidism.Conclusions：131I is safe and effective in treating hyperthyroidism complicated with hepatic dysfunction.
出处
《蚌埠医学院学报》
CAS
2010年第6期562-563,567,共3页
Journal of Bengbu Medical College
基金
安徽省教育厅高等学校自然科学研究资助项目(KJ2009B217Z)
