摘要
目的了解我院2003年1月～2008年12月不同头颈部感染致病菌种类及耐药特征,为临床合理用药提供依据。方法收集我科2003年1月～2008年12月不同头颈部感染患者资料,以其中脓液细菌培养阳性者75例为研究对象,对细菌种类及耐药性进行统计分析。结果 75例标本共培养出84株菌株(其中67例培养出一种细菌,7例培养出两种细菌,1例培养出三种细菌),主要是G+球菌和G-杆菌,其中G+球菌占51.19%,以金黄色葡萄球菌、草绿色溶血性链球菌、表皮葡萄球菌多见;G-杆菌占41.67%,以铜绿假单胞菌、克雷伯氏菌等多见;G+杆菌(如类白喉棒状杆菌)、G-球菌(如多糖奈瑟氏球菌)以及真菌分别占有一定比例。不同原因、不同部位头颈部感染的细菌有所不同,但均以金黄色葡萄球菌、铜绿假单胞菌、草绿色溶血性链球菌最常见。细菌对抗生素的耐药性出现不同程度的变化。不同部位的同一种细菌药敏结果未见明显差异。结论不同原因、不同部位头颈部感染的致病菌种类有所差异;不同的常见致病菌对各种抗菌药物的耐药性出现不同程度的变化。及时的细菌培养和药敏结果有助于指导临床用药。
Objective To serch for infectious pathogens which cause different head and neck infections and analyze their drugresistance characteristics, and provide a basis for rational use of clinical drug. Methods 75 sanies germiculture positive cases were summarized different pathogenic types of head and neck infections and drug resistance characteristics from the First Affiliated Hospital of Anhui Medical University from Jan, 2003 to Dec, 2008. Results 84 bacteria strains were detectable from 75 samples （in which 67 samples were cultured one type of bacteria respectively, 7 samples were cultured two types, and 1 sample has three types）. Cultured bacteria were mainly G^＋ coccus and G bacillus, G^＋ coccus rate was 51.19%, which was Staphylococcus aureus, Grass green hemolytic streptococcus and Staphylococcus epidermidis, G^- bacillus rate was 41.67%, including Pseudomonas aeruginosa, Klebsiella pneumoniae. Apart from G^- coccus and G bacillus, G^＋ bacillus（types of Corynebacterium diphtheriae）. Bacteria infected by various reasons and in different places are different from each other. Staphylococcus aureus, Pseudomonas aeruginosa and Streptococcus viridans were the most common. These pathogens showed a varying responce to drug resistance of different antibiotics. Bacteria infected have no significant differences base on drug resistance analysis and susceptibility results. Conclusion Pathogens could cause head and neck infections in different sources and places. The common pathogens showed a varying responce to drug resistance of different antibiotics. Bacteria detection and drug sensitivity results will contribute to clinical therapy.
出处
《中国中西医结合耳鼻咽喉科杂志》
2010年第3期174-177,180,共5页
Chinese Journal of Otorhinolaryngology in Integrative Medicine
关键词
头颈部感染
致病菌
耐药性
Head and neck infections
Pathogens
drug resistance
