摘要
目的探讨胸部炎性肌纤维母细胞瘤(IMT)的临床特点、处理方法及预后,以提高诊治效果。方法回顾性分析2005年1月至2008年12月外科治疗的10例胸部炎性肌纤维母细胞瘤患者的临床资料,其中男5例,女5例;年龄15～61岁,平均年龄37.5岁。肺部病变患者行肺叶切除加淋巴结清扫术5例;纵隔病变患者完整切除肿瘤4例,部分切除1例。结果全组患者术后恢复顺利,无死亡和围手术期并发症发生。病理检查均未发现淋巴结转移。1例肺部病变患者因病理检查为部分生长活跃,有恶变,术后给予4个周期的化疗;其余患者术后未给予治疗。所有患者通过电话或信件均获得随访,随访时间6个月～4.5年,定期行胸部CT、全身骨显像和腹部超声检查,无肿瘤复发或转移征象。结论炎性肌纤维母细胞瘤临床诊断困难,应按低度恶性肿瘤处理,彻底切除肿瘤以及受侵的组织和器官,可获得良好的治疗效果。
Objective To investigate the clinical characteristics,surgical management and prognosis of inflammatory myofibroblastic tumor in the chest,and improve the efficacy of diagnosis and treatment.Methods From January 2005 to December 2008,we retrospectively reviewed the clinical data of 10 patients with inflammatory myofibroblastic tumor in the chest.The patients included 5 men and 5 women who were at the age of 15 to 61 years old with an average age of 37.5.Five cases of lung lesions underwent lobectomy plus systematic lymph node dissection.Complete resection of mediastinal lesions was performed in 4 cases and partial resection in 1 case.Results All cases recovered successfully with no perioperative complications or death.Pathological examination found no lymph node metastases.A case received postoperative adjuvant chemotherapy for 4 courses because of partial active growth and malignant pathological transformation.The remaining cases were not given treatment after operation.All the patients were followed up by telephone or letter for 6 months to 4.5 years,and were checked up regularly with chest CT,whole body bone scan and abdominal ultrasound.No sign of tumor recurrence or metastasis was found.Conclusion There exists lots of difficulties in clinical diagnosis of inflammatory myofibroblastic tumor and it should be treated as low-grade malignant tumor.Complete removal of the tumor and the tissues and organs invaded can have a good therapeutic effect.
出处
《中国胸心血管外科临床杂志》
CAS
2010年第3期202-205,共4页
Chinese Journal of Clinical Thoracic and Cardiovascular Surgery
