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ABO血型系统诊断新生儿溶血病的实验研究 被引量:11

ABO blood group system diagnosis of neonatal hemolytic disease of experimental study
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摘要 目的:本文通过实验观察拟了解母婴ABO血型不合的新生儿溶血病(HDN)的血清学检测结果。方法:选取市本级医院送我站320例有不同程度黄染或临床疑似为新生儿溶血病的新生儿进行了血清学检测。母婴血型鉴定包括新生儿溶血病三项试验,即直接抗人球蛋白试验、游离抗体试验、抗体释放试验。结果:新生儿溶血病检测阳性占送检标本的71.3%(228/320)。其中出生后0 d~2 d组的送检阳性率为89.2%,出生后3 d~4 d组的送检阳性率为71.0%,出生后5 d~7 d组的送检阳性率为46.9%,出生后8 d~15 d组的送检阳性率为25.4%。结论:血型血清学检验是早期诊断新生儿溶血病的准确方法。抗体释放试验阳性患儿血液中存在的游离抗体有助于判断患儿疾病的发展趋势。 Objective:In this study,the experimental observation of maternal and child to understand the ABO hemolytic disease of the newborn(HDN),as well as the incidence of HDN serological test results.Methods:210 cases in our hospital there are different levels or clinical suspected yellow dye for hemolytic disease of newborn babies had a serological testing.Identification of maternal and child blood group included three trials of neonatal hemolytic disease,that is,direct antiglobulin test,free antibody test,antibody test release.Results:The incidence of hemolytic disease of newborn was 53.1%(109/212).One 0-2d after birth group was 89.2% positive rate,3-4d after birth,the positive rate of group 71.0%,5-7d after birth,the positive rate of group 46.9%,8-15d after birth,the positive rate of group 25.4%.Conclusion:The blood group serology testing for early diagnosis of neonatal hemolytic disease of the exact method.Positive antibody test in children with the release of the existence of the blood of free antibodies in children with the disease will help to determine trends.
作者 詹影影
出处 《中国卫生检验杂志》 CAS 2010年第6期1421-1422,共2页 Chinese Journal of Health Laboratory Technology
关键词 ABO血型系统 新生儿溶血病 ABO blood group system HDN
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