摘要
目的了解本地区产金属β-内酰胺酶的铜绿假单胞菌阳性率及其耐药性。方法 2007年7月～2009年10月本地区住院患者送检标本4247份分离铜绿假单胞菌。采用VITEK2Compact自动微生物分析仪进行细菌鉴定和药敏测定,同时测定MIC。并对其标本来源和病区分布进行了分析。结果产金属β-内酰胺酶的铜绿假单胞菌的分离率为9.77%(415/4247),其中检出率较高的科室为ICU、呼吸内科、普外科、脑外科、骨科。产金属β-内酰胺酶株对其他16种抗生素的耐药性具有特殊性。结论本地区产金属β-内酰胺酶的铜绿假单胞菌检出率较高,分布科室有特殊性,产金属β-内酰胺酶的铜绿假单胞菌对抗生素的耐药性具有特殊性。
Objective To understand the positive rate and its resistance of pseudomonas aeruginosa of metallo- β -lactamase produced in the Xiangnan region. Methods Pseudomonas aeruginosa was isolated from 4247 specimens of inpatients in this region from July 2007 to Oct. 2009. The bacterial identification and the susceptibility determination were carried out by using VITEK 2 Compact automated microbial analyzer,at the same time,with the determination of MIC. And the specimen sources and ward distribution were analyzed. Results The detection rate of pseudomonas aeruginosa was 9.77% （415/4247）, in which departments of higher detection rate covered ICU,respiratory medicine,general surgery,neurosurgery and orthopedics. The resistance rate of strains producing B-metallo-beta-lactamases was higher than that of the strains not producing B-metallo-beta-lactamases to 16 antibiotics. Conclusion The detection rate of Pseudomonas aeruginosa of B-metallo-beta-lactamases was higher in our area,the distribution is different in different wards,and the resistance rate of the strains producing B-metallo-beta-lactamases to antibiotic is higher than that of the strains not producing B-metallo-beta-lactamases.
出处
《中国现代医生》
2010年第16期67-69,共3页
China Modern Doctor
关键词
铜绿假单胞菌
耐药性
金属Β-内酰胺酶
Pseudomonas aeruginosa
Drug resistance
Metallo-beta-lactamase
