摘要
目的:分离鉴定仙鹤草降糖活性部位的化学成分。方法:采用硅胶柱、Sephadex LH-20柱等常压柱色谱手段进行分离纯化,通过理化常数和光谱分析鉴定其结构。结果:从仙鹤草中分得8个化合物,并鉴定为β-谷甾醇(1)、胡萝卜苷(2)、(2R,3R)-(+)-花旗松素(3)、槲皮素-3-O-α-L-鼠李糖苷(4)、槲皮素-3-O-β-D-吡喃半乳糖苷(5)、槲皮素-3-O-β-D-吡喃葡萄糖苷(6)、阿魏酸(7)、没食子酸(8)。结论:化合物3,7,8均为首次从该植物中分离得到。
Objective：To isolate and identify the chemical constituents from the active section with lowering blood sugar of agrimony.Method：The compounds were separated by repeated silica gel,Sephadex LH-20 and HPLC chromatographies.The structures of compounds isolated were identified by analysis of their spectral data and chemical properties.Result：Eight compounds were isolated from the active section with lowering blood sugar of agrimony.And their structures were identified as β-sitosterol（1）,daucosterol（2）,taxifolin（3）,quercetin-3-O-α-L-rhamnopyranoside（4）,hyperin（5）,quercetin-3-O-β-D-glucopyranoside（6）,ferulaic acid（7）,gallic acid（8）.Conclusion：Compounds 3,7,8 are isolated from agrimony for the first time.
出处
《中国实验方剂学杂志》
CAS
北大核心
2010年第6期85-87,共3页
Chinese Journal of Experimental Traditional Medical Formulae
基金
广东省中医药局建设中医药强省科研项目(2009274)
广东食品药品职业学院自然科学基金项目(2009YZ010)
关键词
仙鹤草
降糖
活性成分
agrimony
lowering blood sugar
active substance
