摘要
目的 研究松果体区肿瘤（PRTs）的病理分布特点及不同病理类型的临床特点.方法 回顾性分析南方医院神经外科自2000年1月至2009年1月经手术治疗并取得完整病理资料的133例PRTs患者的临床资料及病理特点.结果 133例患者中生殖细胞肿瘤61例（45.9%）,松果体实质肿瘤17例（12.8%）,神经上皮肿瘤28例（21.1%）,其他肿瘤27例（20.2%）.生殖细胞肿瘤中男女比例为14.25：1,平均15.3岁.松果体实质肿瘤中男女比例为2.4：1,平均24.7岁.神经上皮肿瘤中男女比例为1.15：1,平均28.1岁.有33例血清免疫学检查异常,除1例为转移瘤外,其余均为生殖细胞肿瘤.结论 PRTs病理类型多样,以生殖细胞肿瘤为主;影像学检查、血清免疫学检查及活检均不能准确判断病理类型,积极手术获得完整病理标本对于PRTs的病理研究有重要意义.
Objective To investigate the pathological distribution and clinical characteristics of pineal region tumors （PRTs） with variant pathology.Methods We retrospectively analyzed the clinical and pathological data of 133 patients with PRTs that were performed surgical removal from January 2000 to January 2009 in our hospital.Results Sixty-one patients （45.9%） were diagnosed as having germ cell tumors,17 （12.8%） pineal parenchymal tumors,28 （21.1%） gliomas and 27 （20.2%）other resource tumors.Sex ratio of patients with germ cell tumors,pineal parenchymal tumors and gliomas were 14.25：1 （male：female）,2.4：1 and 1.15：1,respectively; their median ages were 15.3,24.7 and 28.1,respectively.The serum immunologic test showed abnormal results in 33 patients; except for 1 with metastatic tumors,the others were diagnosed as having germ cell tumors.Conclusion PRTs have many pathological types and patients with PRTs are mainly diagnosed as having germ cell tumors.Correct diagnosis can not be made by imaging,serum immunologic test or biopsy, thus,obtaining complete clinical specimen during the total tumor removal is very necessary in studying the pathology of PRTs.
出处
《中华神经医学杂志》
CAS
CSCD
北大核心
2010年第6期614-618,共5页
Chinese Journal of Neuromedicine
