摘要
6α-溴-青霉烷酸二苯甲酯以活性二氧化锰或6%~8%的过氧乙酸氧化。
Two isomers of the key intermediate for semi synthetic β lactamase inhibitors——benzhydryl 6 α penicillanate 1 α (and 1β )oxide were synthesized with mild and safe activated manganese dioxide and 6%~8% peracetic acid in 57% and 75% yields respectively.
出处
《中国医药工业杂志》
CAS
CSCD
北大核心
1999年第1期35-37,共3页
Chinese Journal of Pharmaceuticals
关键词
青霉烷酸
二苯甲酯亚砜
异构体
合成
二氧化锰
benzhydryl 6 α bromopenicillanate 1 oxide,activated manganese oxide,isomer.