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小肠细菌过度生长在肠易激综合征中的研究进展 被引量:10

Advances in Studies on Small Intestinal Bacterial Overgrowth in Irritable Bowel Syndrome
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摘要 肠易激综合征(IBS)是一种常见的功能性胃肠病,其发病机制复杂.目前认为IBS与胃肠动力障碍、内脏高敏感、肠道感染、脑-肠轴功能紊乱、免疫活化等因素有关.最新研究表明小肠细菌过度生长(SIBO)在IBS的发病中亦起重要作用.本文就SIBO在IBS中的研究进展,包括病理生理机制、诊断、治疗等作一综述. Irritable bowel syndrome (IBS) is a common gastrointestinal disorder with complicated mechanisms. Several factors have been identified as etiological factors of IBS, such as altered gastrointestinal motility, visceral hypersensitivity, intestinal infection, abnormal brain-gut interaction and immunological activation, etc. Recent studies have shown that small intestinal bacterial overgrowth (SIBO) also plays an important role in the pathogenesis of IBS. This article reviewed the advances of studies on SIBO in IBS, including pathophysiologic mechanisms, diagnosis and treatment.
机构地区 青海大学医学院
出处 《胃肠病学》 2010年第5期309-311,共3页 Chinese Journal of Gastroenterology
关键词 肠易激综合征 小肠细菌过度生长 肠杆菌科 流行病学 氢呼气试验 治疗 Irritable Bowel Syndrome Small Intestinal Bacterial Overgrowth Enterobacteriaceae Epidemiology Hydrogen Breath Test Therapy
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