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胃癌及癌旁组织中分泌性白细胞蛋白酶抑制因子SLPI的表达 被引量:5

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摘要 维持胃黏膜的正常结构依赖于胃黏膜细胞的凋亡和增殖的动态平衡,这一平衡的失调被认为是胃癌发生及发展的重要机制。分泌性白细胞蛋白酶抑制因子(secretoryleukocytepeptidaseinhibitor,SLPI)属于Kazal型丝氨酸蛋白酶抑制剂家族,具有调控细胞分化增殖的能力。本研究拟通过对胃癌患者组织标本中SLPI表达水平的研究,评价其在胃癌发生、发展中的作用。
出处 《中华内科杂志》 CAS CSCD 北大核心 2010年第6期515-517,共3页 Chinese Journal of Internal Medicine
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