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骨质疏松症合并颈椎病的颈椎椎体形态改变:病例-对照 被引量:8

Morphological changes in cervical vertebral body patients with osteoporosis and cervical spondylosis: Case-control study
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摘要 背景:有学者发现,老年骨质疏松患者的颈椎椎体骨小梁减少、变细、甚至穿孔,那么这种改变是否会导致颈椎椎体变形,又与颈椎病发病有哪些关系呢?目的:通过测量、比较骨质疏松症合并颈椎病后的颈椎形态学改变来探讨二者的关系。方法:以40例腰椎骨密度正常、无颈椎病的体检者为对照组,平均32.5岁;30例确诊的颈椎病为颈椎病组,平均43.6岁;46例颈椎病合并骨质疏松症组为合并骨质疏松症组,平均58.6岁。116例受试者拍摄X射线片。测量椎体高度、椎体矢状径和椎体高度/矢状径比、椎管/椎体矢状径比。结果与结论:与对照组比较,骨质疏松合并颈椎病组的椎体高度下降、矢状径变长(P<0.05),椎管/椎体矢状径比变小(P<0.05),椎体变形以椎体高度下降与矢状径延长而变得扁平为主要特点。提示骨质疏松导致颈椎椎体变形,骨质疏松与颈椎病存在相关性,并可能是颈椎病进展的因素。 BACKGROUND: Some scholars have found that cervical vertebral body bone trabecula was reduced, became thin, even perforated in old patients with osteoporosis. Whether this change will induce cervical vertebral body deformation, and what relationship to the onset of cervical syndrome. OBJECTIVE: To study the relation of cervical spondylotic myelopathy and osteoporosis by measuring and comparing. METHODS: A total of 40 subjects with normal lumbar vertebra density and without cervical spondylosis were enrolled as control group, averagely 32.5 years. A total of 30 patients with cervical spondylosis served as cervical spondylosis group, averagely 43.6 years. Totally 46 patients with cervical spondylosis and osteoporosis served as combined with osteoporosis group, averagely 58.6 years. 116 subjects underwent radiograph. Height and sagittal diameter of the vertebral body, ratio of height to sagittal diameter of the vertebral body, and ratio of sagittal diameter of cervical canal/ vertebra body were measured. RESULTS AND CONCLUSION: Compared with the control group, vertebral height was decreased, and sagittal diameter became longer (P 0.05), and the ratio of sagittal diameter of cervical canal/ vertebra body became smaller (P 0.05) in the combined with osteoporosis group. Vertebral body deformation was characterized by decreased vertebral height and prolonged sagittal diameter became flat. Results suggested that osteoporosis induced cervical vertebral deformation, correlation between osteoporosis and cervical spondylosis, which may be a factor for cervical spondylosis development.
出处 《中国组织工程研究与临床康复》 CAS CSCD 北大核心 2010年第11期2048-2051,共4页 Journal of Clinical Rehabilitative Tissue Engineering Research
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