摘要
在分析中医证候诊断临界值确定方法的基础上,探讨运用类ROC曲线法(受试者工作特性曲线,Receiver Operator Characteristic Curve,简称ROC曲线)确定中医证候诊断临界值的方法,以抑郁症的中医证候为例,在临床流行病学调查资料的基础上,首先求出各证候积分最大值,然后用类ROC曲线法(改良的ROC曲线法)以"积分最大值的35%"为最佳临界值点来确定相应证候诊断的临界值。并提出目前中医证候诊断规范方法的研究,比较合适的方法是以病统证、病证结合,以单一证为研究单元;通过专家问卷来初步确定证候-症状对应关系;用隐变量分析对临床调查资料进行分析,验证并修正证候-症状对应关系,同时确定症状的权重,用类ROC曲线法来确定诊断的临界值。
This study identified the diagnostic critical value of TCM syndrome using quasi Receiver Operator Characteristic（ROC） Curve.Data of depression was collected by clinical epidemiologic survey and maximum of each TCM syndrome value was calculated.Diagnostic critical value was identified using quasi ROC Curve（35% maximum as best critical value）.Method of TCM syndrome diagnostic norms study includes：classifying syndromes by disease,combining disease and syndrome,studying each syndrome,identifying the preliminary corresponding correlation of syndrome and symptom by expert questionnaire,analyzing clinical research data using Latent Variable Analysis,verifying and adjusting syndrome-symptom correlation and identifying weight,identifying diagnostic critical value using quasi ROC Curve.
出处
《中国中医基础医学杂志》
CAS
CSCD
北大核心
2010年第5期358-359,375,共3页
JOURNAL OF BASIC CHINESE MEDICINE
基金
国家高技术研究发展计划(863计划)(2008AA02Z406)
国家杰出青年科学基金资助项目(30825046)
关键词
证候
诊断临床值
受试者工作特性曲线
抑郁症
Syndrome
Diagnostic Critical Value
Receiver Operator Characteristic Curve
Depression
