摘要
目的探讨重症医学科(ICU)关于呼吸机相关性肺炎的病原学、危险因素、发病机制、诊断及治疗等,以便引起广大医护人员的重视,减少该病的发生率,提高治愈率。方法收集本院重症医学科2008年1月～2009年12月机械通气患者146例,其中发生VAP例数为61。结果本组VAP的发生率为41.78%,病死率36.07%。共检出病原菌89株,其中G-杆菌71.92%、G+菌11.23%、真菌16.85%。非VAP组病死率17%。结论 VAP的主要致病茵为G-杆菌;G+菌、真菌感染比例也逐渐增加,临床上合理应用抗生素,积极治疗原发病,缩短上机时间、避免医源性危险因素,加强免疫治疗,可以降低呼吸机相关性肺炎的发生。
Objective To investigate the pathogen,risk factors,pathogenesis,diagnosis and treatment of ventilator-associated pneumonia（VAP） patient s in intensive care unit（ICU）,which makes medical staff pay more attention to it and is helpful to decrease the incidence of VAP and raise cure rate.Methods A retrospective study was made on 146 patients with mechanical ventilation,patients were hospitalized between January 2008 and December 2009,including 61 VAP cases.Results The incidence of VAP was 41.78%,mortality was 36.07%.The main 89 pathogens of VAP included gram-negative bacteria（71.92%）,gram-positive bacteria（11.23%） and fungi（16.85%）;The mortality of non-VAP was 17%.Conclusion the main pathogens of VAP was gram-negative bacteria.The incidence of gram-positive bacteria and fungi increased.It could be helpful to decrease the incidence of VAP by the reasonable use of antibiotics,active treatment of the primary affection,shorten the time of MV,avoid the iatrogenic risk factors,boost Immunotherapy.
出处
《当代医学》
2010年第16期13-14,共2页
Contemporary Medicine
关键词
呼吸机相关性肺炎
病原学
感染
临床分析
Ventilator-associated pneumonia
pathogenesis
infection
Clinical analysis
