摘要
胰源性区域性门静脉高压症主要表现为脾大、胃底静脉曲张并可致消化道出血,临床较为少见。多种胰腺疾病如慢性胰腺炎、胰体尾肿瘤等均可导致此症,其病理基础为上述胰腺病变导致脾静脉狭窄或栓塞,而脾动脉供血正常,脾充血肿大,脾静脉血回流由胃短静脉代偿,致胃底部形成区域性门静脉高压症。对于肝功能正常而合并脾大的消化道出血者应考虑到胰源性区域性门静脉高压症的可能。脾切除可有效控制出血,治疗上还应考虑针对胰腺原发疾病的治疗,该病的预后主要取决于胰腺的原发疾病。
Pancreatic sinistral portal hypertension is a rare syndrome presented with splenomegaly, gastric varices and gastrointestinal haemorrhage, which due to a primary pancreatic diseases such as chronic pancreatitis, pancreatic tumors. The pathology arises in the pancreas and results in compression of the splenic vein, while the splenic artery blood supply is normal, which consequently result in congestive enlargement of the spleen and back pressure changes in the left portal system. Pancreatic sinistral portal hypertension should be considered in the presence of gastrointestinal bleeding with normal liver function and unexplained splenomegaly. Splenectomy can effectively control the bleeding, however treatment of pancreatic primary disease should be involved. The overall prognosis for patients with sinistral portal hypertension is clearly dependant on the primary pathology.
出处
《中国实用外科杂志》
CSCD
北大核心
2010年第6期449-451,共3页
Chinese Journal of Practical Surgery
关键词
胰源性静脉高压
胃底静脉曲张
消化道出血
脾切除术
pancreatic sinistral portal hypertension
gastroesophageal varices
gastrointestinal bleeding
splenectomy
