摘要
目的探讨缓解期抑郁症患者认知功能状况，为临床干预提供依据。方法将57例缓解期抑郁症患者设为研究组，选取51名健康体检者设为对照组；应用探究性眼动分析和事件相关电位对两组进行检测分析。结果探究性眼动分析检测，研究组凝视点和反应探索分值均显著低于对照组（P〈0．01）；事件相关电位P300检测，研究组靶刺激-P3潜伏期延长、波幅降低，与对照组比较均有极显著性差异（P〈0．01）。结论抑郁症患者缓解期的认知功能仍有轻度损害，应注重缓解期的维持和巩固治疗。
Objective To study the cognitive function of the depression patients in remission. Methods In order to explore the cognitive function of the remitted depression patients, exploratory eye movement （EEM） and event-related potentials （P300） were conducted in 51 healthy persons and 57 depression patients in remission. Results Compared with the healthy ones, patients with depression in remission had lower NEF and RSS, and prolonged amputide and lower latency（P〈0. 01）. Conclusion Depression patients have mild cognitive impairment during the period of remission. The maintenance and consolidation therapy should be paid more attention to them.
出处
《临床心身疾病杂志》
CAS
2010年第3期255-256,共2页
Journal of Clinical Psychosomatic Diseases
