摘要
目的探讨直肠间质瘤的临床诊断及治疗方法。方法分析直肠间质瘤的临床表现、病理特点及治疗情况。结果直肠间质瘤的临床表现主要包括大便次数增多、排尿困难、血便及肛门疼痛等。7例均经病理确诊，免疫组化检测CD117（＋）7例、CD34（＋）6例。术前考虑为GIST者1例，本组均经手术治疗，其中Dixon术4例，Miles术2例，经肛门肿瘤局部切除1例。随访6—120个月，死亡1例，其余6例均存活且无复发。结论直肠间质瘤临床较少见，生物学行为多变，具有潜在恶性，确诊需病理形态学及免疫组化证实，手术是唯一能治愈的方法，根治性切除较局部切除效果好。
Objective To analyze the features of clinical diagnosis and treatment of rectal gastroin- testinal stromal tumor（GIST）. Methods The clinical and pathological deta and theatment of 7 cases from January 1999 to December 2008 were analyzed retrospectively. Results The most common clinical mani- festations and symptoms of rectal stromal tumors were increased frequency of defecation, urinary retention, bloody stool and anal pain. Rectal GIST were diagnosed by pathology for all cases. Immunohistochemical results showed CDll7（ ＋ ） in 7 cases and CD34（ ＋ ） in 6 cases,while there was no difference on clinical manifestations. Only 1 case was diagnosed as rectal GIST preoperatively. All cases underwent surgical treatment, of which anterior resection of the rectum （Dixon） was performed in 4cases, abdominoperineal resection（Miles） in 2 cases and regional resection in 1 case. During 6 to 120 months of follow -up,6 ca- ses survived without recurrence and 1 cases died. Conclusion Rectal GIST has a low prevalence clinically, varied biological behavior, and potential malignancy. Diagnosis of this disease depends on pathological and immunohistochemical results. Surgical resection is the only curable method and the effect of radical excision is better than regional excision.
出处
《医学新知》
CAS
2010年第2期106-108,共3页
New Medicine
关键词
直肠间质瘤
诊断
治疗
rectal GIST
diagnosis
treatment
