摘要
下载PDF阅读器目的 探讨聚焦超声（focused ultrasound）治疗外阴白色病变（white lesion of vulva）的临床疗效.方法 选取2005年8月至2009年8月,在本院接受聚焦超声治疗的186例确诊为外阴白色病变患者为研究对象,其年龄为13～72岁,病程为2.5个月～30.0年.治疗后定期随访,观察患者症状、体征的变化（本研究程序符合本院人体试验委员会所制定的伦理学标准,得以该委员会批准,并与患者签署临床研究知情同意书）.结果 本组186例患者中,22例（11.8%）失访.接受随访的164例中,治愈为128例（78.0%）,其中64例为鳞状上皮增生型,46例为硬化性苔藓型,18例为混合型;有效为35例（21.3%）,无效为1例（0.6%）,总有效率为99.4%.所有随访病例中,未发现复发者.不同病理学类型及不同病程外阴白色病变患者对聚焦超声治疗效果比较,差异无显著意义（P＞0.05）.结论 聚焦超声治疗外阴白色病变安全、有效、无创.
Objective To explore the efficacy of white lesion of vulva treated with focused ultrasound. Methods From August 2005 to August 2009, 186 cases with white lesion of vulva, aged 13-72 years old, were treated with focused ultrasound in the Department of Obstetrics and Gynecology, Center Hospital of Panzhihua. Informed consent was obtained from all participants. The course of white lesion of vulva of these 186 patients was 2.5 months to 30 years. The changes of symptoms and signs before and after the treatment were observed to evaluate clinical efficacy and reliability. Results Of all 186 cases, 164 （88.2%） were fol- lowed up after the treatment, and the total effective rate was 99.4% （185/186）. Of the 164 follow-up cases, 128 cases （78.0%） were cured, in which 64 were squamous hyperplasia, 46 were lichen sclerosus and 18 were lichen sclerosus with squamous hyperplasia; 35 cases （21.3%） improved. Only 1 （0.6%） had no response to the therapy, who was diagnosed as vulvar carcinoma by biopsy at the next year after the treat ment. There was no significant difference among different pathological types group and different courses of disease after reeeving focused ultrasound treatment （P〉0.05）. Conclusion Focused ultrasound is a safe and effective method to treat white lesion of vulva with no wound.
出处
《中华妇幼临床医学杂志（电子版）》
CAS
2010年第3期195-197,共3页
Chinese Journal of Obstetrics & Gynecology and Pediatrics(Electronic Edition)
关键词
聚焦超声
外阴白色病变
focused ultrasound
white lesion of vulva
