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优泌乐25和优泌林70/30对口服药物继发失效的2型糖尿病的临床疗效观察 被引量:3

Comparison of the Effect of Humalog 75/25 and Humulin 70/30 in the Treatment of Patients with Type 2 Diabetes Mellitus after Oral Agent Failure
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摘要 [目的]观察优泌乐25和优泌林70/30治疗2型糖尿病的疗效.[方法]80例口服药继发失效的2型糖尿病(T2DM)患者,随机分成2组(各40例)分别给予优泌林70/30和优泌乐25治疗12周,比较两组的疗效.[结果]两组空腹血糖(FPG)、平均餐后2小时血糖(2hPG)较治疗前显著下降(P〈0.01),优泌乐组2hPG下降较优泌林70/30下降更为显著(P〈0.05).[结论]优泌乐25能更加有效地控制餐后血糖,减少低血糖发生. [Objective] To assess the efficacy of Humalog 75/25 and Humulin 70/30 in the treatment to type 2 diabetes mellitus(DM). [Methods] A total of 80 patients with type 2 DM after secondary failure to oral hypoglycaemic agents were randomized to Humalog 75/25 group( n = 40) and Humulin 70/30 group( n = 40). After 12 weeks of treatment, the effects were compared between two groups. [Results] The levels of fasting plasma glucose (FPG) and the average 2-hour postprandial blood glucose (2hPG) after treatment were signifi- cantly lower than before treatment ( P 〈0.01). The decrease in Humalog 75/25 group was more significant than that in Humulin 70/30 group. [Conclusion] Humalog 75/25 for controlling postprandial blood glucose and reducing the occurrence of hypoglycemia is more effective than Humulin 70/30.
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出处 《医学临床研究》 CAS 2010年第5期841-842,共2页 Journal of Clinical Research
关键词 糖尿病 非胰岛素依赖型/药物疗法 胰岛素/投药和剂量 降血糖药/投药和剂量 diabetes mellitus,non-insuliwdependent/DT insulin/AD hypoglyeemic agents/AD
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参考文献6

  • 1冯凭.对2型糖尿病患者启动胰岛素治疗的思考[J].国际内分泌代谢杂志,2008,28(1):70-72. 被引量:16
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二级参考文献3

  • 1[1]UK Prospective Diabetes Study(UKPDS)Group Intentive blood glucose control with sulphonylureas or insulin compared with conventional treatment ang risk of complication in patients with type 2 diabetea(UKPDS33).Lanct 1998;352:837. 被引量:1
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