摘要
[目的]观察优泌乐25和优泌林70/30治疗2型糖尿病的疗效.[方法]80例口服药继发失效的2型糖尿病(T2DM)患者,随机分成2组(各40例)分别给予优泌林70/30和优泌乐25治疗12周,比较两组的疗效.[结果]两组空腹血糖(FPG)、平均餐后2小时血糖(2hPG)较治疗前显著下降(P〈0.01),优泌乐组2hPG下降较优泌林70/30下降更为显著(P〈0.05).[结论]优泌乐25能更加有效地控制餐后血糖,减少低血糖发生.
[Objective] To assess the efficacy of Humalog 75/25 and Humulin 70/30 in the treatment to type 2 diabetes mellitus(DM). [Methods] A total of 80 patients with type 2 DM after secondary failure to oral hypoglycaemic agents were randomized to Humalog 75/25 group( n = 40) and Humulin 70/30 group( n = 40). After 12 weeks of treatment, the effects were compared between two groups. [Results] The levels of fasting plasma glucose (FPG) and the average 2-hour postprandial blood glucose (2hPG) after treatment were signifi- cantly lower than before treatment ( P 〈0.01). The decrease in Humalog 75/25 group was more significant than that in Humulin 70/30 group. [Conclusion] Humalog 75/25 for controlling postprandial blood glucose and reducing the occurrence of hypoglycemia is more effective than Humulin 70/30.
出处
《医学临床研究》
CAS
2010年第5期841-842,共2页
Journal of Clinical Research