摘要
目的探讨CT与SPECT在常染色体显性多囊肾(ADPKD)治疗中的作用。方法回顾性分析89例ADPKD患者的病历资料,观察各期患者术前CT表现特点及术前、术后SPECT肾动态显像的变化。结果患者术前CT显示双肾体积增大,肾实质内多发大小不等的囊性低密度影,增强扫描后肾盂与囊肿对比明显。SPECT肾动态显像结果显示Ⅰ、Ⅱ、Ⅲ期患者术前肾小球滤过率(GFR)分别为(49.47±9.93)ml/min、(30.59±8.16)ml/min、(14.84±6.22)ml/min,术后分别为(52.14±8.67)ml/min、(43.77±9.33)ml/min、(14.65±5.61)ml/min。Ⅱ期患者术后GFR显著高于术前(P<0.05),Ⅰ、Ⅲ期患者术后GFR与术前相比,差异无统计学意义(P>0.05)。结论联合应用CT及SPECT有利于掌握肾脏形态及功能的综合信息,选择最佳手术时机及合理治疗方案。
Objective To explore the value of CT and SPECT renal dynamic imaging in the treatment of autosomal dominant polyeystic kidney disease （ADPKD）. Methods Clinical data of 89 patients with ADPKD were analyzed retrospectively. CT features and changes of SPECT renal dynamic imaging pre-operation and post-operation in different stages of ADPKD were investigated. Results The enlarged volume of kidneys and multiple cystic low-density lesions of different sizes within renal parenchyma were displayed on plain CT images. On enhanced CT images, renal pelvis was enhanced but cysts were still hypodense. The preoperative GFR of stage I , Ⅱ , Ⅲ was （49.47±9.93）ml/min, （30.59±8.16）ml/min and （14.84±6.22）ml/min, respectively, whereas postoperative GFR of stage I , II , Ⅲ was （52.14±8.67）ml/min, （43.77±9.33） ml/min and （I4.65 ± 5.61） ml/min, respectively. In stage Ⅱ patients, postoperative GFR was significantly higher than preoperative GFR （P〈0. 05）. However, there was no statistical difference between pre operation and post-operation GRF in patients with stage I and Ⅲ （P〉0.05）. Conclusion CT combined with SPCET renal dynamic imaging is helpful to provide valuable information of renal morphology and function for urologists to choose optimal operation timing and therapeutic schemes,
出处
《中国医学影像技术》
CSCD
北大核心
2010年第5期921-924,共4页
Chinese Journal of Medical Imaging Technology
基金
山东省自然科学基金(Y2008C80)
