摘要
目的:通过对白内障患者房水中梅毒特异性和非特异性抗体的检测,探讨梅毒是否通过房水传播。方法:对2003年以来准备接受白内障手术的1 673例患者进行常规的传染四项检查,包括乙肝表面抗原(HBsAg)、丙型肝炎抗体(HCV抗体)、梅毒抗体(TP抗体)、艾滋病抗体(HIV抗体)四项指标,并统计梅毒发生的阳性率;应用特异性抗体试验—金免疫层析试验(GICA)和非特异性抗体试验—甲苯胺红不加热血清试验(TRUST)检测梅毒患者血清及房水中的抗体。结果:1 673例白内障手术患者有21例患者血液中初筛出梅毒抗体,阳性率1.26%;21例梅毒抗体阳性患者血清中GICA阳性检出率为95.24%(20/21),房水中为33.33%(7/21),两者比较差异有统计学意义(P<0.05);同组患者血清中TRUST阳性检出率为52.38%(11/21),房水中为9.52%(2/21),两者比较差异有统计学意义(P<0.05)。结论:近年来,梅毒感染阳性率相对稳定,并且梅毒可能不通过房水传播。
Objective：To probe the positive rates of syphilis in cataract operational patients and to detect the specific and unspecific antibody in blood and aqueous humor of syphilis patients for providing basis of aqueous humor route of transmission of syphilis.Method：1 673 patients being accepted cataract operation from 2003 were confirmed by preoperative serological tests of these four infectious diseases including HBsAg、HCV Antibody、TP Antibody and HIV Antibody.Infection ratio of syphilis in cataract operational patients were analyzed.The specific and unspecific antibody in blood and aqueous humor of syphilis patients was detected by Gold-Immunochromatographic Assay （GICA） and Toluidine Red Unheated Serum Test（TRUST）.Result：In 1 673 patients being accepted cataract operation,21 cases patients had syphilis antibody in blood.In the 21 cases syphilis patients blood serum,the positive ratio of GICA was 95.24%（20/21）while that ratio in aqueous humor was 33.33%（7/21）;The ratio was observed in two groups with significant difference（P〈0.05）;In the same syphilis patients,the positive ratio in blood of TRUST was 52.38%（11/21）while that ratio in aqueous humor was 9.52%（2/21）,the ratio was observed in two groups with significant difference（P〈0.05）.Conclusion：Recently,positive rates of syphilis infection was relatively stabilizing and the syphilis may not infect through aqueous humor.
出处
《内蒙古医学杂志》
2010年第4期406-408,共3页
Inner Mongolia Medical Journal
关键词
梅毒
眼科手术
白内障
房水
血清学诊断
Syphilis
Ophthalmic operation
Cataract
Aqueous humor
Serological diagnosis
