摘要
目的 探讨胰腺癌高危评分模型的临床应用价值.方法 利用评分模型对我院2006年10月至2009年10月疑诊的75例胰腺癌患者进行前瞻性研究.结果 胰腺癌患者临床三大症状依次为上腹痛55.88%（38/68）、消瘦19.12%（13/68）、黄疸19.12%（13/68）.B超、薄层增强CT、内镜逆行胰胆管造影（ERCP）、磁共振胰胆管造影（MRCP）诊断胰腺癌阳性率分别为47.06%（32/68）、88.24%（60/68）、87.88%（29/33）、87.1%（27/31）,薄层增强CT与ERCP、MRCP在诊断胰腺癌方面差异无统计学意义,但均优于B超检查（P均〈0.05）;以胰腺癌高危评分≥27分为标准,则诊断胰腺癌的准确性为86.67%（65/75）,手术切除率仅为17.39%（4/23）.未能发现早期胰腺癌.结论 胰腺癌高危评分模型诊断胰腺癌有一定的临床应用价值,但在诊断早期胰腺癌方面尚需进一步研究.
Objective To discuss the clinical value of hish risk scoring model and screening strategy in the diagnosis of pancreatic cancer.Methods 75 cases of suspected pancreatic cancer were studied prospectively with this model from Oct.2006 to Oct.2009.Results Abdominal pain,weight loss and jaundice were the most common symptoms,which was 55.88%（38/68）,19.12%（13/68） and 19.12%（13/68） respectively.The positive rates of B type ultrasonography,abdominal spiral CT,ERCP and MRCP in the diagnosis of pancreatic cancer were 47.06% （32/68）,88.24%（60/68）,87.88%（29/33） and 87.1%（27/31）,there was no obvious differences in the abdominal spiral CT,ERCP and MRCP,but better than B type ultrasonography（P〈0.05）.With a cutoff value of 27 points,the accuarcy of the scoring model were 86.67%（65/75）,resectability was only 17.39%（4/23）,no early stage pancreatic cancer were inspected.Conclusions The high risk scoring model provides a simple and feasibly way to screen pancreatic cancer,but need study more in the diagnosis of early stage pancreatic cancer.
出处
《中国综合临床》
2010年第4期366-368,共3页
Clinical Medicine of China
基金
珠海市科技计划项目（PC20061078）
关键词
胰腺癌
高危评分模型
Pancreatic cancer
High risk scoring model
