摘要
目的探讨以不明原因发热（FUO）为首发表现的恶性肿瘤患者的病因及临床特征。方法回顾性分析我院2000年1月～2007年12月间以FUO为首发表现的69例恶性肿瘤患者的病因、诊断方法和临床表现。结果69例恶性肿瘤患者男女比例为3．06：1，淋巴瘤最多见（占56．5％），肺癌次之（占24．6％）。多部位穿刺活检有助于淋巴瘤明确诊断，淋巴瘤患者PPD试验阳性率低于结核病，但差异无显著性；89．7％（35／39）的患者有血象下降改变，其中三系细胞均下降比例最高，占36．4％（14／39），83．9％（26／31）的患者乳酸脱氢酶（LDH）增高。所有肺癌患者均合并有阻塞性肺炎。结论以不明原因发热为首发表现的恶性肿瘤患者中淋巴瘤居首位，肺癌其次，仔细寻找线索有助于明确诊断。
Objective To investigate the etiopathogenisis and and clinical features of patients with malignant diseases initial presenting as fever of unknown origin （FUO）. Methods The clinical datas including the cause, methods of diagnosis and clinical characters were retrospectively analyzed in patients with malignant diseases and initial presenting as FUO in Chinese PLA general hospital from January 2000 to December 2007. There were 69 cases fulfilled the criteria. Results The male-to-female ratio was 3.06： 1. Lymphoma was the most frequent ,and the second was lung cancer. Multiple biopsies was helpful for diagnosis, the positive rate of PPD test in tuberculosis was higher than in ]ymphoma, but there was no statistical significance. There were decreasing of WBC in 35/39 （ 89.7% ）. Increasing lactate dehydrogen- ase （LDH） was found in 26/31 （83.9%） ;All lung cancer had obstructive pneumonia. Conclusions The first cause of malignant diseases initial presenting as FUO was lymphoma, and the second cause was lung cancer. Searching for probably clue of maligancy was helopful for diagnosis of FUO.
出处
《临床内科杂志》
CAS
2010年第5期313-315,共3页
Journal of Clinical Internal Medicine
关键词
发热
回顾性研究
肿瘤
Fever
Retrospective study
Malignancy
