摘要
目的评价瞬态声诱发耳声发射(transient otoacoustic emission,TEOAE)与自动判别听性脑干反应(auto-auditory brainstem-respons,AABR)在新生儿听力复筛中联合使用的必要性及可靠性。方法对1469例新生儿,初筛采用TEOAE,复筛采用TEOAE和AABR联合筛查。应用SPSS11.0软件对TEOAE和AABR联合筛查的相关性及差异性进行分析。结果 1469例新生儿中,1374例TEOAE初筛通过者,复筛时TEOAE和AABR均通过1351例,均未通过5例,TEOAE未通过16例,AABR未通过2例,TEOAE和AABR的相关性和差异性分析均有统计学意义(P<0.001,P=0.0010);95例TEOAE初筛未通过者,复筛时TEOAE和AABR均通过69例,均未通过11例,TEOAE未通过14例,AABR未通过1例,TEOAE和AABR的相关性分析和差异性分析均有统计学意义(P<0.001,P=0.0008)。最终确诊4例感音神经性听力下降,1例传导性听力下降。结论在对新生儿进行听力筛查时,初筛应用TEOAE,复筛应用TEOAE和AABR联合筛查方案可有效减少漏诊和误诊。
Objective To study a comprehensive analysis of the reliability of combined TEOAE with AABR in newborn hearing screening. Methods 1 469 subjects in this study were selected from the PLA general hospital in the first hearing screening by TEOAE and the combined TEOAE and AABR were administered in the rescreening. Results In these 1 469 newborns, 1 374 subjects who passed the initial screening also passed the rescreening by means of TEOAE and AABR. The variance analysis of combined TEOAE and AABR in rescreening was significant （P〈0. 001, P=0. 0010）. 95 subjects who failed TEOAE screening and the correlation analysis of the combined TEOAE and AABR in re--screening was significant （P〈0. 001, P= 0. 0008）. Finally, 4 subjects were confirmed with sensorineural hearing loss, and one subject had conductive hearing loss. Conclusion In the screening program, TEOAE should be used for the initial screening and the combined use of TEOAE and AABR for the rescreening to ensure the accurate detection rate of deafness in newborns for less misdiagnosis.
出处
《听力学及言语疾病杂志》
CAS
CSCD
北大核心
2010年第3期233-235,共3页
Journal of Audiology and Speech Pathology
基金
国家863项目(2006AA02Z181)
国家自然基金重点项目(30830104),国家自然基金面上项目(30672310,30771857&30771203)
高等学校全国优秀博士学位论文作者专项资金资助项目(200463)
国家973项目(2007CB507400)
北京市重大专项课题项目(7070002)
国家“十一五”科技支撑计划(2006BAI02B06&2007BAI18B12)联合资助
