摘要
目的探讨肺灌注显像Meyer评分在肺栓塞患者疗效评价中的临床价值。方法接受抗凝或溶栓治疗的30例肺栓塞患者，均在治疗前1～2d内完成肺灌注／通气显像，治疗后1～2周内复查肺灌注显像，治疗前后的灌注图像不分先后随机编号，由2名核医学专业医师对图像进行定性分析，然后对治疗前后灌注图像进行Meyer评分半定量分析。结果30例肺栓塞患者经临床治疗后，其中15例局部血流灌注有明显改善，8例轻度改善，5例未见有变化，2例有恶化。其中，23例血流灌注有改善者治疗前为0．45±0．14，治疗后为0．22±0．11，治疗前后分值的变化有统计学差异（t=11．627，P〈O．05）；7例无改善患者治疗前为0．23±0．15，治疗后为0．23±0．17，治疗前后分值的变化无统计学差异（t=O．143，P〉O．05）；但两组改善率间比较有统计学差异（t=2．410，P〈O．05）。结论Mever评分能很好的评价治疗前后肺部血流灌注变化的情况，对肺栓塞患者的疗效评价具有一定的临床价值。
Objective To assess the clinic value of Meyer method of pulmonary perfusion imaging in evaluation of the therapeutic effect of pulmonary embolism. Methods Thirty patients who were diagnosed as pulmonary embolism and received anticoagulant or thrombolytic therapy. All patients received pulmonary ventilation/perfusion imaging before treatment within 1 to 2 days and received pulmonary perfusion imaging again after treatment within 1 to 2 weeks. The two images obtained in each patient were scored together. Meyer method of semi-quantitative visual evaluations were used. Results Thirty patients after therapy, among 15 patients obviously improve of pulmonary perfusion, 8 patients lightly improve, 5 patients no change and 2 patients aggravation. By Meyer method, the 23 patients of improvement group, the score of before treatment （0.45±0.14）, the score of after treatment （0.22±0.11）, the score was significant change （t=1 1.627, P〈0.05） . the 7 patients of no change group, the score of before treatment （0.23 ±0.15）, the score of after treatment （0.23-±0.17）, the score was not significant change （t=0.143, P〉0.05）. the improvement rate of two groups were significant change （t=2.410, P〈0.05）. Conclusion The Meyer method could effectively evaluate the pulmonary perfusion change after the treatment of pulmonary embolism, and there was clinic value in evaluation of the therapeutic effect of pulmonary embolism.
出处
《国际放射医学核医学杂志》
2009年第5期265-267,共3页
International Journal of Radiation Medicine and Nuclear Medicine
关键词
肺栓塞
肺灌注显像
Meyer评分
Pulmonary embolism
Pulmonary perfusion imaging
Meyer method
