摘要
目的:探讨肝胆管结石合并胆管癌的临床表现特征和诊治经验。方法:分析了自2001年1月到2009年8月我院收治的30例肝胆管结石合并胆管癌患者的临床资料。结果:肝胆管结石合并胆管癌术前确诊10例,术中病理检查确诊14例,术后病理检查发现6例。左肝胆管癌16例,占53.3%,右肝胆管癌7例占23.3%,肝门部胆管癌5例占16.7%,其余2例为左右肝都有。肿瘤根治性切除术17例(56.7%),姑息性手术9例(30%),单纯活检4例(13.3%)。在30例随访资料中,根治性切除术者平均存活时间26个月。存活1年以上10例,2年以上5例,3年以上2例;姑息治疗者术后平均生存9个月;其余的≤4个月。结论:胆石症状易反复发作,胆道病史较长大于10年且术前CA199>2500 ng/mL的患者应高度怀疑合并有胆管癌。
Objective： To analysis the clinical characteristics,diagnosis,and treatment of cholelithiasis complicated with cholangiocaminoma.Methods： Clinical and pathological data were analysed retrospectively on 30 cases of hepatolithiasis complicated with cholangiocarcinoma.Results： Ten（33%） patients of patients were diagnosed as cholangiocarcinoma preoperatively.Tumor occurring in left intrahepatic ducts,right intrahepatic ducts,and hilar bile duct was 53.3%,23.3% and 16.7% respectively.Other two cases are in both left and right hepatic lobes.17（56.7%） cases underwent radical resection,and their mean survival time was 26 months;9（30%） cases underwent palliative operation,and their mean survival time was 9 months;Other 4 cases were under no surgical treatment whose survival time was less than 4 months.Conclusion： The symptom of hepatolithiasis appears repeatedly.If patients with a history of hepatolithiasis more than 10 years and their preoperative CA199 was more than 2500 ng/mL are under the risk of cholangiocareinoma.
出处
《华西医学》
CAS
2010年第1期129-131,共3页
West China Medical Journal
关键词
胆结石
胆管癌
cholelithiasis
cholangiocarcinoma
