摘要
目的:分析围绝经期抑郁症状与血清性激素水平的关联性,为早期诊断,寻找围绝经期妇女身心保健的有效对策提供重要依据。方法:采用抑郁自评量表(SDS),对在某院就诊的150名围绝经期妇女进行调查,SDS评分≥53分被定义为存在抑郁症状。按有无抑郁症状分为抑郁组和非抑郁组;利用放免法检测血清雌二醇、孕酮、促卵泡激素、促黄体生成素水平;应用SPSS13.0进行录入数据和统计分析。结果:两组的年龄之间具有可比性(P>0.05);抑郁组雌二醇、孕酮水平低于非抑郁组,而促卵泡激素水平高于非抑郁组,差异均具有统计学意义(P<0.05);两组间促黄体生成素水平无显著性差异(P>0.05)。结论:围绝经期抑郁的发生与血清雌二醇、孕酮水平降低和促黄体生成素水平升高有关。
Objective：To analyze the relevance of peri-menopausal period depressive symptoms and serum sex hormone levels to provide an important effective response for early diagnosis of peri-menopausal period and physical and mental health promotion of peri-menopausal women.Methods：150 peri-menopausal women treated in HeFei Maternal and Child Hospital were investigated by self-rating depression scale （SDS）.SDS score ≥53 points is defined as the existence of depressive symptoms. According to whether the depressive symptoms, 150 peri-menopausal women were divided into depression group and non-depression group; Estradiol, progesterone, follicle-stimulating hormone, luteinizing hormone levels of serum were measured by radioimmunoassay. Results： Depression group and the non-depressed group were no statistically significant difference between age, so the two groups can be compared （P〉0.05）; Depression group gave significant lower Estradiol and progesterone levels than non-depressed group （P 〈0.05） and gave significant higher follicle-stimulating hormone level than non-depression group （P〈 0.05）. luteinizing hormone level was no significant difference between the two groups （P〉0.05）. Conclusions：The occurrence of depression in peri-menopausal period is associated with a higher level of estradiol, progesterone and a lower level of luteinizing hormone of serum
出处
《安徽卫生职业技术学院学报》
2010年第2期29-30,共2页
Journal of Anhui Health Vocational & Technical College
关键词
围绝经期抑郁症状
性激素水平
研究
Peri-menopausal Period Depressive Symptoms
Serum Sex Hormone Levels
Research
