摘要
目的:找出抗组胺药临床应用特点和发展趋势,探讨其合理选用.方法:就马鞍山皮肤病防治所近5年(1993~1997年)口服抗组胺药的消耗量以DDD_s·d^(-1)为单位进行比较,计算各药消耗金额占品服抗组胺药总金额的百分比.结果:特非那丁、酮替芬的临床应用逐年上升,以特非那丁上升幅度最大;特非那丁、阿司咪唑、西替利嗪等第2代H_1受体桔抗剂消耗金额较多.结论:分析表明,特非那丁、酮替芬、氯苯吡胺为马鞍山皮肤病防治所主要的口服抗组胺药.
To identify the trend of clinical use of antihistamine agents and better utilization of the drugs, the consumption of different oral antihistamine agents in our hospital during recent 5 years were analyzed in terms of the definite daily dose (DDDs)/day. The percentage of money paid for each category in light of total amount of money paid for all antihistamine agents was calculated. Our results showed that the clinical use of terfenadine and ketotifen increased over the past five years, with the terfenadine being on the top of the list. More money was spent for 'second-generation' antihistamine agents, i.e. terfenadine, astemizole and cetirizine. In our institute, the terfenadine, ketotifen and chlorpheniramine were most commonly used antihistamine agents.
出处
《药物流行病学杂志》
CAS
1999年第1期34-35,共2页
Chinese Journal of Pharmacoepidemiology
关键词
抗组胺药
日限量
药物流行病学
合理用药
Antihistamine agents
Definite daily dose
Pharmacoepidemiology
Drug utilization