摘要
目的:建立HPLC法测定洛伐他汀含量的不确定度评估的方法。方法:通过建立HPLC含量测定法的数学模型,找出影响不确定度的因素,并对各个不确定度的分量进行评估。结果:计算各分量的不确定度,由此计算合成不确定度,最终给出测定结果的扩展不确定度和置信水平。结论:建立的不确定度评估方法可用于HPLC法测定洛伐他汀含量的不确定度评估。
Objective：To establish a method of uncertaintY evaluation for the determination of Lovastatin by HPLC.Methods： The calculation formula for the uncertainty was deduced in the procedure of assy for lovastatin.Results：Each component of uncertainty was calculated by analyzing the variable parameters among the procedures.The combined uncertainty and confidence level were finally obtained by synthesizing the uncertainties of various component variables.Conclusion： This method is appropriate to be used in the uncertainty evaluation for the determination of Lovastatin by HPLC.
出处
《中国当代医药》
2010年第13期48-49,共2页
China Modern Medicine
