摘要
目的 :观察参麦注射液治疗新生儿缺氧缺血性脑病 (HIE)合并心肌损害 30例的临床疗效。方法 :治疗组 30例在常规治疗基础上用参麦注射液 2 m L/ (kg·d)加入 10 %葡萄糖溶液 5 0 m L中静滴 ,每日 1次 ,疗程 7～ 10天。对照组 33例 ,仅用常规治疗。结果 :治疗组的显效率 5 3% (16/30 )和总有效率 80 % (2 4 / 30 )均明显高于对照组的 2 1%和 5 5 % (7/ 33和 18/ 33) ,P<0 .0 1和 P<0 .0 5 ;治疗组心率、心电图、心肌酶学恢复时间比对照组显著缩短 (P<0 .0 1) ;治疗组神经系统主要症状和体征消失时间比对照组显著缩短 (P<0 .0 1)。结论 :参麦注射液治疗 HIE合并心肌损害疗效满意。
Objective:To investigate the clinical effects of Shenmai injection on hypoxic-ischemic encephalopathy(HIE) and myocardial injury in neonates Methods:30 patients were treated with Shenmai Injection of 2 mL/(kg·d) in 50 mL 10% glucose intravenously guttae once a day for 7～10 days on a routine basis 33 cases in the control group were treated only with routine therapy Results:The significant effictive rate(53%)and total effective rate(80%) were higher in the treatment group than in the control group(21% and 55%), P <0 01 or P <0 05 Compared with the control group,the treatment group had shorter time of recovery of heart rate,electrocardiogram,myocardial enzyme and for the disappearance of neurological symptoms and signs Conclusion:Treatment of HIE and myocardial injury with Shenmai Injection shows satisfactory clinical effects
出处
《新医学》
1998年第12期627-628,共2页
Journal of New Medicine
关键词
缺氧缺血性脑病
心肌损害
新生儿
参麦注射液
Neonate Hypoxic-ischemic encephalopathy Myocardial injury Shenmai injection
