摘要
目的探讨2型糖尿病(T2DM)患者血浆炎症因子(IL-1β、IL-6、TNF-α、C-RP)水平与糖代谢及胰岛素抵抗(IR)的关系。方法分别检测60名健康者、60例T2DM患者血浆中的炎症因子水平及其他相关指标,并进行统计分析。结果 T2DM组各炎症因子、FPG水平均高于正常对照组;TNF-α与C-RP的水平与HbA_1c及IR指数呈正相关(P<0.05)。结论血浆IL-1β、IL-6、TNF-α、C-RP与T2DM的发生发展相关,TNF-α、C-RP是T2DM糖代谢紊乱和IR的重要指标。
Objective To study the relationship of inflammatory factors with glucose metabolism and insulin resistance in patients with type 2 diabetes mellitus. Methods We measured the levels of serum irflammatory factors and oth The levels of inflammatory factors, er parameters in 60 cases of T2DM and 60 healthy people. Results FPG were higher in T2DM correlated wi F-a and C-RP th insulin group than in normal group. The levels resistance index （IRI） （ P 〈0.05 ）. closely related to incidence and the development of T2DM. TNF-α and C-RP are the important indexes of glucose metabolic disorders and insulin resistance in T2DM.
出处
《中国糖尿病杂志》
CAS
CSCD
北大核心
2010年第4期253-254,共2页
Chinese Journal of Diabetes
关键词
糖尿病
2型
炎症因子
胰岛素抵抗
Diabetes meUitus, type 2
Inflammatory factor
Insulin resistance
