摘要
目的探讨冠状动脉介入治疗术后简便、有效的经口水化治疗方法,提高水化治疗效果,预防造影剂肾病。方法将320例接受冠状动脉介入治疗患者随机分为自由饮水组和定量饮水组各160例,自由饮水组术后3h内嘱患者尽量饮水,24h总饮水量大于2000ml;定量饮水组术后3h内饮水量以造影剂用量为指导,造影剂用量100ml以内饮水1000ml,造影剂用量101～200ml饮水1500ml,术后24h总饮水量大于2000ml。结果使用造影剂100ml以内两组术后3h入量;使用造影剂101～200ml两组术后3h、24h入量,术后4h、24h尿量,术后第1天尿微量白蛋白比较,差异有统计学意义(P<0.05,P<0.01)。结论术后3h内根据造影剂用量指导饮水,可减轻冠状动脉介入术后患者造影剂相关肾损伤,尤其对造影剂用量为101～200ml的患者。
Objective To explore a simple and effective oral hydration regimen for preventing contrast-induced nephropathy after percutaneous coronary intervention （PCI）. Methods A total of 320 patients receiving PCI were randomized into two groups of 160. The control group received routine oral hydration regimen, and patients were asked to drink as much as possible within 3 h after PCI; while their counterparts in the experimental group were given contrast dose-guided oral hydration regimen, patients receiving less than 100 ml or 101-200 ml contrast were asked to drink 1 000 ml or 1 500 ml of water within 3 h after PCI respectively. The total volume of water intake within 24 h after PCI was more than 2 000 ml in both groups. Results The fluid intake volume within 3 h after PCI in patients receiving less than 100 ml contrast had significant difference between the two groups （P〈0.01）. In patients receiving 101-200 ml contrast, statistical differences were found in the fluid intake volume within 3 h and 24 h after PCI, in the urine volume within 4 h and 24 h, and in the content of urine microalbumin on the 1st day after PCI between the two groups （P〈0.05 ,P〈0.01）. Conclusion Contrast dose-guided oral hydration within 3 h after PCI can reduce contrast-induced kidney damage, especially for patients received 101-200 ml contrast.
出处
《护理学杂志（综合版）》
2010年第5期22-24,共3页
Journal of Nursing Science
关键词
冠心病
介入治疗
造影剂
造影剂肾病
饮水量
coronary artery disease
intervention
contrast
contrast-induced nephropathy
volume of water intake
