摘要
目的:观察丹红注射液联合前列地尔治疗不稳定型心绞痛的疗效。方法:74例不稳定型心绞痛患者,随机分为对照组(37例)和观察组(37例)。对照组为常规治疗组,观察组在常规治疗组的基础上加用丹红注射液联合前列地尔。在治疗4周后分别对两组临床疗效、心电图及动态心电图变化进行分析,并观察患者的安全性和耐受性。结果:观察组与对照组相比,心绞痛的控制有效率明显增加(P<0.05),心电图改善明显增加(P<0.05),动态心电图缺血发作次数显著减少(P<0.05)。结论:在常规治疗的基础上加用丹红注射液联合前列地尔能更有效地控制不稳定型心绞痛,且患者耐受性好,无不良反应发生。
OBJECTIVE：To evaluate the efficacy of Danhong injection combined prostaglandin E1 in the treatment of patients with unstable angina pectoris（UAP）.METHODS：Seventy four patients with UAP were randomly assigned to receive either routine therapy alone（control group,n = 37） or routine therapy plus Danhong injection 40 mL·d-1 and prostaglandin E1 10 μg·d-1（trial group,n = 37）.After treatment for 4 weeks,the clinical efficacy,ECG and Holter ECG monitoring of the two groups were recorded and the drug safety and drug tolerance in patients were observed.RESULTS：After treatment for 4 weeks,compared with the control group,the trial group showed a significantly higher efficacy with regard to the management of angina pectoris（P 0.05）,significantly better ECG improvement（P 0.05） and a significantly lower frequency of attacks of myocardial ischemia（P 0.05）.CONCLUSION：Addition of Danhong injection and prostaglandin E1 to routine therapy can more effectively keep UAP under control which are well-tolerate yet without adverse drug reactions.
出处
《中国医院用药评价与分析》
2010年第4期352-353,共2页
Evaluation and Analysis of Drug-use in Hospitals of China
关键词
丹红注射液
前列地尔
不稳定型心绞痛
Danhong injection
Prostaglandin E1
Unstable angina pectoris（UAP）
