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新型隐球菌脑膜炎46例 被引量:2

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摘要 目的总结分析新型隐球菌性脑膜炎的临床特征及治疗方法。方法对我院1999年1月至2009年10月收治的46例新型隐球菌脑膜炎患者临床及预后资料进行回顾性分析。结果46例患者中合并其他疾病者21例,占45.7%;15例患者在病前有明确的鸽子接触史,占32.6%;有误诊史16例。所有患者均给予系统治疗,有3例患者入院2周后由于经济原因放弃治疗出院,并失去随访,其余43例患者以两性霉素B联合5-氟胞嘧啶(5-FC)联合治疗。结果10例痊愈,14例好转,10例转院失访,11例死亡,病死率24.2%,未愈1例。结论新型隐球菌脑膜炎误诊率高,各种原因所致的免疫缺陷是引发隐脑的主要危险因素;尽早明确诊断、联合两性霉素B与5-FC抗真菌治疗、积极控制颅内压是降低病死率、改善预后的关键。
作者 沈海滨
出处 《临床医学》 CAS 2010年第4期58-59,共2页 Clinical Medicine
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参考文献6

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