摘要
通过5-甲基-4-乙氧羰基呋喃氨基腈与芳醛反应,制得希夫碱,再采用NaBH4还原,合成了8个新型的5-甲基-4-乙氧羰基呋喃氨基腈衍生物.其结构经1HNMR,IR,EI-MS分析证实.生物活性测试结果表明,目标化合物具有一定的抗菌活性.
Reaction of 5-methyl -4 – ethoxycarbonyl furan aminonitriles with aromatic aldehydes gives Schiff base,which is reduced with NaBH4 to provide 8 new 5-methyl-4-ethoxycarbonyl furan aminonitriles derivatives. Their structures are characterized by IR,1HNMR,EI-MS. The preliminary bioassays indicate that these compounds possess certain fungicidal activities against five kinds of fungi at a concentration of 200 mg/L.
出处
《河南师范大学学报(自然科学版)》
CAS
CSCD
北大核心
2010年第2期123-125,共3页
Journal of Henan Normal University(Natural Science Edition)
基金
湖北省科技厅重点项目(D20092806)
关键词
呋喃氨基腈衍生物
合成
抗菌活性
furan aminonitriles derivative
synthesis
fungicidal activity